
Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced...
Recurrent Skin CancerSquamous Cell Carcinoma of the SkinThe goal of this clinical research study is to learn if giving Iressa (Gefitinib or ZD1839) with surgery and/or radiation will help to control squamous cell carcinoma of the skin. The safety of this treatment will also be studied

Gemcitabine and Docetaxel in Treating Patients With Recurrent or Persistent Uterine Cancer
Recurrent Uterine Corpus SarcomaUterine CarcinosarcomaThis phase II trial is studying how well giving gemcitabine together with docetaxel works in treating patients with recurrent or persistent uterine cancer. Drugs used in chemotherapy, such as gemcitabine and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Recurrent Salivary Gland CancerRecurrent Squamous Cell Carcinoma of the Hypopharynx32 moreThis phase II trial studies how well lapatinib ditosylate works in treating patients with metastatic or recurrent head and neck cancer. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer
Metastatic Squamous Neck Cancer With Occult PrimaryRecurrent Metastatic Squamous Neck Cancer With Occult Primary14 moreLapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for their growth. This phase II trial is studying how well lapatinib works in treating patients with recurrent and/or metastatic head and neck cancer.

Duloxetine Versus Placebo in the Prevention of Recurrence of Major Depressive Disorder
Depressive DisorderMajorThe purpose of this study is to assess the efficacy and safety of duloxetine compared with placebo in the prevention of depressive recurrences among patients with recurrent major depressive disorder.

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors...
Recurrent Childhood Anaplastic AstrocytomaRecurrent Childhood Brain Stem Glioma6 moreThis phase I/II trial studies lapatinib to see how well it works in treating young patients with recurrent or refractory central nervous system (CNS) tumors. Lapatinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.

Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian...
Recurrent Fallopian Tube CarcinomaRecurrent Ovarian Carcinoma1 moreSorafenib may stop the growth of tumor cells by blocking the enzymes necessary for their growth and by stopping blood flow to the tumor. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving sorafenib together with chemotherapy may kill more tumor cells. This randomized phase II trial is studying how well giving sorafenib together with paclitaxel and carboplatin works in treating patients with recurrent ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. (Sorafenib only group closed as of 10/10/2008).

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver Cancer6 moreLapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. This phase II trial is studying how well lapatinib ditosylate works in treating patients with unresectable liver or biliary tract cancer

Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary...
High-grade Salivary Gland CarcinomaHigh-grade Salivary Gland Mucoepidermoid Carcinoma8 morePhase II trial to study the effectiveness of lapatinib in treating patients who have recurrent and/or metastatic adenoid cystic cancer or other salivary gland cancers. Lapatinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.

SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell CarcinomaRecurrent Metastatic Squamous Neck Cancer With Occult Primary20 moreThis phase II trial is studying how well SB-715992 works in treating patients with recurrent or metastatic head and neck cancer. Drugs used in chemotherapy, such as SB-715992, work in different ways to stop tumor cells from dividing so they stop growing or die.