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Active clinical trials for "Asthma"

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Symbicort in Asthmatic Children - SEEDLING

Asthma

The purpose of this study is to compare Symbicort with budesonide alone and formoterol alone in the treatment of asthma in children aged 6 to 11 years

Completed5 enrollment criteria

Relative Bronchodilating Effects of Formoterol When Administered Via Symbicort Pressurized Metered-dose...

Stable Asthma

The purpose of this study is to compare the therapeutic effects of formoterol in Symbicort with formoterol in Oxis Turbuhaler for the treatment of adults with stable asthma.

Completed5 enrollment criteria

A Phase 1 Study of AIR645 in Healthy Subjects and Subjects With Controlled Asthma

Asthma

This is a phase one study to evaluate the safety, tolerability, and bioavailability of nebulized AIR645.

Completed20 enrollment criteria

Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate...

AsthmaAirway Inflammation

This is a 2-week double-blind, placebo-controlled, parallel group study comparing the anti-inflammatory effects of low, medium, and high dose mometasone furoate/formoterol fumarate (MF/F) metered dose inhaler (MDI) formulation and medium dose mometasone furoate (MF) dry powder inhaler (DPI) and MDI formulations in adults and adolescents with persistent allergic asthma.

Completed20 enrollment criteria

This Study Compared an in Home Asthma Management Program Provided by Nurses or Respiratory Therapist...

Asthma

This study compared an in-home asthma management program provided by nurses or respiratory therapists to see if those receiving program had fewer hospitalizations, clinic and emergency room visits and higher levels of satisfaction and health related quality of life.

Completed2 enrollment criteria

Efficacy of Symbicort pMDI Administered Once Daily in Children and Adolescents During 12 Weeks -...

Asthma

The purpose of this study is to compare Symbicort with budesonide alone for the treatment of asthma in children aged 6 to 15 years

Completed5 enrollment criteria

Long-Term Safety of Symbicort in Asthmatic Children - SAPLING

Asthma

The purpose of this study is to assess the safety of Symbicort compared to Pulmicort in asthmatic children aged 6 to 11 years

Completed5 enrollment criteria

Safety and Tolerability Study of Levalbuterol HFA Compared to Racemic Albuterol HFA in Subjects...

Asthma

The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI.

Completed23 enrollment criteria

CARE Network Maintenance Versus Intermittent Inhaled Steroids in Wheezing Toddlers (MIST)

Asthma

Asthma affects about 4 million children in the United States and is a leading cause of hospitalizations and school absenteeism. Continuous wheezing in very young children may develop into asthma. Low doses of inhaled corticosteroids (ICS) are commonly prescribed to treat children with particularly bad wheezing episodes. This study will compare the safety and effectiveness of low doses of ICS taken daily versus higher doses of ICS taken only during respiratory tract illnesses for toddlers with continuous wheezing or coughing illnesses.

Completed31 enrollment criteria

Effects of Montelukast in Children With Asthma

Asthma

Leukotriene receptor antagonists (LTRAs) reduce fractional exhaled nitric oxide (FENO) concentrations in children with asthma, but the effect of LTRA withdrawal on FENO and lung function is unknown. We will aim to study the effect of treatment and withdrawal of montelukast, a LTRA, on airway inflammation as reflected by FENO and lung function in children with asthma. A double-blind, randomized, placebo controlled, parallel group study will be undertaken in 18 atopic children with mild persistent asthma who will be treated with oral montelukast (5 mg/day for 4 weeks) and 18 atopic children with mild persistent asthma who will receive matching placebo. A follow-up visit will be performed 2 weeks after montelukast or placebo withdrawal.

Completed10 enrollment criteria
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